Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 16/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327484 | 0.72 | CYP19A1 (0.60) | ESR1CYP19A1SHBGMEN1LMNA | |
| SCHEMBL7145526 | 0.72 | CYP19A1 (0.60) | ESR1CYP19A1SHBGMEN1LMNA | |
| SCHEMBL13327487 | 0.72 | CYP19A1 (0.60) | ESR1CYP19A1SHBGMEN1LMNA | |
| SCHEMBL3338391 | 0.72 | CYP19A1 (0.60) | ESR1CYP19A1SHBGMEN1LMNA | |
| SCHEMBL13642659 | 0.70 | G6PD (0.56) | ESR1CYP19A1SHBGSERPINA6MEN1 | |
| SCHEMBL13642708 | 0.70 | G6PD (0.56) | ESR1CYP19A1SHBGSERPINA6MEN1 | |
| SCHEMBL14193750 | 0.68 | ESR1 (0.42) | ESR1 | |
| SCHEMBL1126907 | 0.68 | G6PD (0.70) | ESR1SHBGSERPINA6MEN1LMNA | |
| SCHEMBL3670416 | 0.68 | G6PD (0.70) | ESR1SHBGSERPINA6MEN1LMNA | |
| SCHEMBL14193758 | 0.68 | G6PD (0.70) | ESR1SHBGSERPINA6MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070055072-A1 | Process for preparing guggulsterones and guggulsterol | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055072-A1 | Process for preparing guggulsterones and guggulsterol | CYP17A1, CYP46A1, HSD17B7 | ESR1 366/4885CYP19A1 30/4885SHBG 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.