SCHEMBL14599185

SCHEMBL14599185

Cc1ccc([N+](=O)[O-])c2cnncc12

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HSD17B10 Q99714 1/20 0.44
TSHR P16473 8/20 0.43
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 3/20 0.43
RECQL P46063 1/20 0.43
CTSB P07858 2/20 0.42
CTSH P09668 1/20 0.42
TDP1 Q9NUW8 3/20 0.42
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.39
NOS1 P29475 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13483429 0.80 MAPT (0.52) SMN1; SMN2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL98882 0.76 TDP1 (0.61) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL8404446 0.76 CYP1A2 (0.47) KMT2AHSD17B10TSHRCYP3A4ALDH1A1
SCHEMBL1561998 0.72 TSHR (0.60) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL3614154 0.72 NOS1 (0.53) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL9689065 0.72 MAPT (0.53) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL922796 0.71 ALDH1A1 (0.62) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL17553044 0.70 TDP1 (0.53) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL28307480 0.69 TDP1 (0.57) SMN1; SMN2MEN1KMT2AHSD17B10TSHR
SCHEMBL10613846 0.69 ALDH1A1 (0.41) MEN1KMT2ATSHRCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed
US-20070003882-A9 Photothermographic material, and image forming method using same FUKUI KOUTA 2007-01-04 US disclosed