Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CAD | P27708 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 7/20 | 0.39 |
| ▸ | METAP1 | P53582 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837118 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL28999753 | 0.84 | CAD (0.55) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL10897143 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL1331748 | 0.79 | LMNA (0.53) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL1330728 | 0.79 | LMNA (0.53) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL1332017 | 0.79 | LMNA (0.53) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL1332187 | 0.79 | LMNA (0.53) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL81193 | 0.79 | LMNA (0.53) | ALDH1A1LMNAHSD17B10CADALOX15 | |
| SCHEMBL14523473 | 0.78 | TSHR (0.41) | ALDH1A1HSD17B10CADALOX15MGAM | |
| SCHEMBL3787404 | 0.77 | LMNA (0.51) | ALDH1A1LMNAHSD17B10CADALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034329-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF AMYLOID-BETA-PEPTIDE RELATED DISORDERS | EXONHIT THERAPEUTICS SA (FR) | 2007-03-29 | — | — | WO | disclosed |