SCHEMBL14601686

SCHEMBL14601686

O=S(=O)(Nc1ccccc1-n1cccc1)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.49
CCR9 P51686 3/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 1/20 0.48
PKM P14618 2/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC40A1 Q9NP59 1/20 0.44
NAMPT P43490 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.43
KEAP1 Q14145 1/20 0.43
ELANE P08246 1/20 0.42
PRTN3 P24158 1/20 0.42
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26536719 0.81 MCOLN3 (0.70) FFAR4KMT2AGAAPKMMCOLN3
SCHEMBL9908753 0.81 PKM (0.64) KMT2APKMMCOLN3L3MBTL1NAMPT
SCHEMBL5822509 0.80 PKM (0.57) KMT2AGAAPKMMCOLN3L3MBTL1
SCHEMBL29087421 0.79 KMT2A (0.64) FFAR4CCR9KMT2AGAAPKM
SCHEMBL14601694 0.79 FFAR4 (0.53) FFAR4CCR9KMT2AGAASLC40A1
SCHEMBL10143422 0.79 FFAR4 (0.57) FFAR4CCR9KMT2AGAASLC40A1
SCHEMBL14458258 0.78 NAMPT (0.51) KMT2AGAAPKMMCOLN3L3MBTL1
SCHEMBL7569763 0.78 FFAR4 (0.59) FFAR4CCR9KMT2AGAASLC40A1
SCHEMBL6818040 0.75 KMT2A (0.52) FFAR4CCR9KMT2AGAASLC40A1
SCHEMBL15821484 0.75 ALDH1A1 (0.59) CCR9KMT2AGAAL3MBTL1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021509-A1 Phosphate transport inhibitors SLC34A2, SLC34A1, SLC20A1 FFAR4 2368/4885CCR9 4370/4885KMT2A 4634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.