Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.51 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355074 | 0.84 | MCOLN3 (0.70) | MCOLN3L3MBTL1PKMMAPTGAA | |
| SCHEMBL29978755 | 0.84 | MCOLN3 (0.74) | MCOLN3L3MBTL1PKMGAAMCOLN2 | |
| SCHEMBL23043740 | 0.84 | MCOLN3 (0.74) | MCOLN3L3MBTL1PKMGAAMCOLN2 | |
| SCHEMBL23043676 | 0.82 | L3MBTL1 (0.79) | MCOLN3L3MBTL1PKMGAAMCOLN2 | |
| SCHEMBL29978358 | 0.82 | L3MBTL1 (0.79) | MCOLN3L3MBTL1PKMGAAMCOLN2 | |
| SCHEMBL14601686 | 0.81 | FFAR4 (0.49) | MCOLN3L3MBTL1PKMMAPTTP53 | |
| SCHEMBL23379815 | 0.81 | MCOLN3 (0.66) | MCOLN3L3MBTL1PKMMAPTGAA | |
| SCHEMBL26919920 | 0.80 | MAPT (0.47) | MCOLN3L3MBTL1PKMMAPTTP53 | |
| SCHEMBL31017284 | 0.80 | MAPT (0.47) | MCOLN3L3MBTL1PKMMAPTTP53 | |
| SCHEMBL23043601 | 0.80 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | MCOLN3 3187/4885L3MBTL1 104/4885PKM 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.