Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601738 | 0.82 | RAD51 (0.54) | ALDH1A1LMNARAD51POLBMAPT | |
| SCHEMBL14601740 | 0.81 | L3MBTL1 (0.56) | ALDH1A1LMNARAD51GAAMAPT | |
| SCHEMBL23853937 | 0.80 | RAD51 (0.76) | ALDH1A1LMNARAD51GAAMAPT | |
| SCHEMBL7580299 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBGAACCR2 | |
| SCHEMBL96167 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNAPOLBGAAMAPT | |
| SCHEMBL7571637 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBGAAMAPT | |
| SCHEMBL5227535 | 0.75 | ALDH1A1 (0.69) | ALDH1A1LMNAPOLBMAPTIDH1 | |
| SCHEMBL23852173 | 0.75 | RAD51 (0.72) | ALDH1A1LMNARAD51GAAPKM | |
| SCHEMBL7573014 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBGAAMAPT | |
| SCHEMBL6831222 | 0.75 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | ALDH1A1 2163/4885LMNA 4385/4885RAD51 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.