Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14603130 | 0.90 | SIGMAR1 (0.54) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL5648368 | 0.90 | SIGMAR1 (0.54) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL4968962 | 0.80 | SIGMAR1 (0.52) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL14641489 | 0.79 | CASP3 (0.61) | — | |
| SCHEMBL14603132 | 0.79 | CASP3 (0.61) | — | |
| SCHEMBL14603128 | 0.79 | CASP3 (0.61) | — | |
| SCHEMBL5649936 | 0.78 | SCN9A (0.42) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL5649938 | 0.78 | SCN9A (0.42) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL7145780 | 0.76 | SIGMAR1 (0.43) | SIGMAR1TMEM97HTR1ACHRM5ADRA2A | |
| SCHEMBL24848142 | 0.76 | FKBP1A (0.46) | HTTFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |