Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368459 | 0.83 | PER2 (0.45) | FKBP1ANPC1RAB9ASMN1; SMN2CASP3 | |
| Hydrochloric Acid SCHEMBL5555279 | 0.82 | FKBP1A (0.54) | FKBP1ASMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL22981228 | 0.81 | NPC1 (0.49) | FKBP1AHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5551252 | 0.81 | ALDH1A1 (0.43) | FKBP1ANPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8082401 | 0.81 | SMN1; SMN2 (0.44) | FKBP1ANPC1RAB9ASMN1; SMN2CASP3 | |
| Hydrochloric Acid SCHEMBL8082397 | 0.80 | SMN1; SMN2 (0.43) | FKBP1ANPC1RAB9ASMN1; SMN2CASP3 | |
| Hydrochloric Acid SCHEMBL8082404 | 0.80 | SMN1; SMN2 (0.43) | FKBP1ANPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL2070172 | 0.80 | FKBP1A (0.54) | FKBP1ASMN1; SMN2ALDH1A1NPSR1MAPT | |
| SCHEMBL14603128 | 0.78 | CASP3 (0.61) | CASP3ALDH1A1CPB1ACE | |
| SCHEMBL14603132 | 0.78 | CASP3 (0.61) | CASP3ALDH1A1CPB1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002388-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002388-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NSD2, NSD1, NSD3 | FKBP1A 3573/4885HTT 3569/4885NPC1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.