Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161298 | 0.73 | MAPT (0.43) | MAPTNPSR1ALDH1A1CYP3A4POLB | |
| SCHEMBL30700955 | 0.73 | ALDH1A1 (0.59) | MAPTNPSR1ALDH1A1CYP3A4POLB | |
| SCHEMBL29276996 | 0.73 | ALDH1A1 (0.59) | MAPTNPSR1ALDH1A1CYP3A4POLB | |
| SCHEMBL11139031 | 0.73 | ACHE (0.52) | MAPTNPSR1ALDH1A1CYP3A4POLB | |
| SCHEMBL30436671 | 0.73 | ACHE (0.52) | MAPTNPSR1ALDH1A1CYP3A4POLB | |
| SCHEMBL11957899 | 0.73 | ACHE (0.52) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL12154783 | 0.72 | HTR3E (0.41) | MEN1KMT2AMAPTHTR3EHTR3B | |
| SCHEMBL13969472 | 0.72 | KDM4E (0.45) | MAPTALDH1A1POLBGAATSHR | |
| Hydrochloric Acid SCHEMBL5428742 | 0.71 | MAPT (0.46) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL16372580 | 0.71 | TUBB4A (0.49) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757579-A1 | Primary 2,6-disubstituted para-phenylenediamines and their uses for dyeing keratin fibres | L'Oréal (FR) | 2007-02-28 | — | — | EP | disclosed |