Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23694613 | 0.82 | KCNMA1 (0.47) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL25021088 | 0.78 | KCNMA1 (0.55) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL25020407 | 0.78 | KCNMA1 (0.55) | KCNMA1RAB9AGAASMN1; SMN2ESR1 | |
| SCHEMBL25873809 | 0.76 | KCNMA1 (0.50) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL25873798 | 0.76 | KCNMA1 (0.50) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL19970064 | 0.76 | KCNMA1 (0.47) | KCNMA1RAB9ASMN1; SMN2ESR1POLB | |
| SCHEMBL24492760 | 0.75 | KCNMA1 (0.49) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL15445028 | 0.74 | KCNMA1 (0.55) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL26907914 | 0.74 | KCNMA1 (0.42) | KCNMA1RAB9AMGAMAMY1AGAA | |
| SCHEMBL18703939 | 0.74 | GRM2 (0.52) | KCNMA1RAB9AGAASMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022529-A2 | METHOD OF TREATING INFLAMMATORY DISEASES | ARRAY BIOPHARMA INC. (US) | 2007-02-22 | — | — | WO | disclosed |