Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26907873 | 0.81 | MAPT (0.35) | KMT2ARAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL27117751 | 0.81 | KCNMA1 (0.43) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL26907967 | 0.80 | KCNMA1 (0.41) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL14610056 | 0.74 | KCNMA1 (0.54) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL26907875 | 0.74 | KMT2A (0.41) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL26907944 | 0.73 | SMN1; SMN2 (0.43) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL23694613 | 0.68 | KCNMA1 (0.47) | KCNMA1KMT2ARAB9ACYP4Z1ESR1 | |
| SCHEMBL25020407 | 0.66 | KCNMA1 (0.55) | KCNMA1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL25021088 | 0.66 | KCNMA1 (0.55) | KCNMA1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL26907908 | 0.65 | SMO (0.33) | KCNMA1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116882-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2024-04-11 | — | — | US | claimed |
| EP-4286374-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-12-06 | — | — | EP | claimed |
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| US-20240116882-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2024-04-11 | — | — | US | disclosed |
| EP-4286374-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-12-06 | — | — | EP | disclosed |
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116882-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | ENPP1, ENPP3, TPP1 | KCNMA1 2059/4885KMT2A 2922/4885RAB9A 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.