Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25873798 | 0.79 | KCNMA1 (0.50) | KCNMA1ALDH1A1LMNARAB9ATSHR | |
| SCHEMBL14610056 | 0.74 | KCNMA1 (0.54) | KCNMA1MAPTALDH1A1LMNAHTT | |
| SCHEMBL19704930 | 0.73 | KCNMA1 (0.47) | GRM2KCNMA1MAPTALDH1A1HPGD | |
| SCHEMBL20821940 | 0.72 | KCNMA1 (0.46) | GRM2KCNMA1MAPTALDH1A1HPGD | |
| SCHEMBL19848254 | 0.72 | L3MBTL1 (0.60) | KCNMA1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL19915941 | 0.72 | L3MBTL1 (0.50) | GRM2KCNMA1MAPTALDH1A1HPGD | |
| SCHEMBL17950009 | 0.71 | KIF11 (0.53) | GRM2KCNMA1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL25873809 | 0.71 | KCNMA1 (0.50) | KCNMA1MAPTALDH1A1LMNARAB9A | |
| SCHEMBL24401805 | 0.70 | ALDH1A1 (0.45) | GRM2KCNMA1MAPTALDH1A1HPGD | |
| SCHEMBL22328685 | 0.70 | SMN1; SMN2 (0.47) | KCNMA1MAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150578-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-04-05 | — | — | EP | disclosed |