Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441804 | 0.88 | PARP1 (0.59) | PIM1KMT2AKDM4ENNMTCCNC | |
| SCHEMBL12548430 | 0.84 | PIM1 (0.62) | PIM1KMT2AKDM4ELMNAPARP1 | |
| SCHEMBL4823327 | 0.82 | PIM1 (0.69) | PIM1KMT2AKDM4ECCNCCDK8 | |
| SCHEMBL3182339 | 0.82 | PIM1 (1.00) | PIM1KMT2AKDM4EPARP1ALDH1A1 | |
| SCHEMBL935079 | 0.82 | PIM1 (0.54) | PIM1KMT2AKDM4ENNMTCCNC | |
| SCHEMBL16228010 | 0.80 | PIM1 (0.57) | PIM1KMT2AKDM4ELMNANNMT | |
| SCHEMBL13977541 | 0.80 | PIM1 (0.67) | PIM1KMT2AKDM4ECCNCCDK8 | |
| SCHEMBL3956008 | 0.79 | PIM1 (0.57) | PIM1ALDH1A1 | |
| SCHEMBL8490359 | 0.79 | PIM1 (0.65) | PIM1KMT2AKDM4ELMNAPARP1 | |
| SCHEMBL1088781 | 0.77 | KDM4E (0.67) | PIM1KMT2AKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116581-B | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2021-06-08 | — | — | CN | claimed |
| CN-111116581-A | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2020-05-08 | — | — | CN | claimed |
| US-20240390328-A1 | PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES | Research & Business Foundation Sungkyunkwan University (KR) | 2024-11-28 | — | — | US | disclosed |
| CN-112342380-B | Application method of hydrophobic extractant in cloud point extraction system | 北京大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-111116581-B | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-111116581-B | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-111116581-B | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112342380-A | Application method of hydrophobic extractant in cloud point extraction system | 北京大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-111116581-A | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116581-A | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116581-A | 2, 9-diamide-1, 10-phenanthroline compound, and synthesis method and application thereof | 清华大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-103044420-A | Phenanthroline derivative, as well as preparation method and application thereof | UNIV SHANXI | 2013-04-17 | — | — | CN | disclosed |
| WO-2007022307-A2 | LIGANDS FOR METAL IONS AND METHODS FOR MAKING AND USING THE SAME | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240390328-A1 | PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES | SARS1, GTF3C4, GTF3C5 | PIM1 879/4885KMT2A 4026/4885KDM4E 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.