Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170409 | 0.87 | KDM4E (0.68) | PIM1KDM4EKMT2AMMP2ALDH1A1 | |
| SCHEMBL7143621 | 0.87 | KDM4E (0.68) | PIM1KDM4EKMT2AMMP2ALDH1A1 | |
| SCHEMBL27283354 | 0.86 | KDM4E (0.66) | PIM1KDM4EKMT2AMMP2ALDH1A1 | |
| SCHEMBL28798022 | 0.86 | KDM4E (0.66) | PIM1KDM4EKMT2AMMP2ALDH1A1 | |
| SCHEMBL3956008 | 0.79 | PIM1 (0.57) | PIM1ALDH1A1 | |
| SCHEMBL14610232 | 0.79 | PIM1 (0.68) | PIM1PARP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL4823327 | 0.79 | PIM1 (0.69) | PIM1PARP1KDM4EKMT2AMMP2 | |
| SCHEMBL3182339 | 0.79 | PIM1 (1.00) | PIM1PARP1KDM4EKMT2AMMP2 | |
| Phthalic Acid SCHEMBL30909153 | 0.78 | MGAM (0.66) | PIM1KDM4EKMT2AALDH1A1 | |
| Phthalic Acid SCHEMBL27503113 | 0.78 | MGAM (0.66) | PIM1KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999041239-A1 | B CELL INHIBITORS | NOVARTIS AG (CH) | 1999-08-19 | — | — | WO | disclosed |