SCHEMBL14612349

SCHEMBL14612349

O=C(NCC(O)CO)C(O)(F)F

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
EGFR P00533 1/20 0.30
SRC P12931 1/20 0.30
CA2 P00918 1/20 0.30
LOX P28300 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27081436 0.85 ALDH1A1 (0.46) ALDH1A1LMNACYP2C19HIF1APOLB
SCHEMBL3139336 0.85 ALDH1A1 (0.46) ALDH1A1LMNACYP2C19HIF1APOLB
SCHEMBL20692421 0.79 LMNA (0.33) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL26198162 0.77 LMNA (0.36) ALDH1A1LMNACYP2C19HIF1APOLB
SCHEMBL25590205 0.77 LMNA (0.36) ALDH1A1LMNACYP2C19HIF1APOLB
SCHEMBL3464664 0.77 LMNA (0.36) ALDH1A1LMNACYP2C19HIF1APOLB
SCHEMBL22181736 0.76 LMNA (0.31) LMNACYP2C19HIF1A
SCHEMBL2745754 0.73 CA2 (0.35) ALDH1A1LMNACYP2C19HIF1AKDM4E
SCHEMBL12532987 0.73
SCHEMBL1565854 0.73 ALDH1A1 (0.52) ALDH1A1POLBSMN1; SMN2HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7184197-B2 High performance capsules for electrophoretic displays SIPIX IMAGING, INC. (US) 2007-02-27 US disclosed