Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14612780 | 0.89 | GPR119 (0.36) | GPR6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3158355 | 0.85 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DGPR119 | |
| SCHEMBL13902610 | 0.83 | FAAH (0.36) | GPR6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3163770 | 0.74 | GPR119 (0.49) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL3903282 | 0.74 | GPR6 (0.44) | GPR6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5201546 | 0.74 | GPR119 (0.48) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| Potassium Ion SCHEMBL5201540 | 0.73 | GPR119 (0.48) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL3151620 | 0.72 | STS (0.55) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL14214812 | 0.72 | GPR119 (0.49) | GPR119 | |
| SCHEMBL3157416 | 0.71 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027185-A1 | Antithrombotic aromatic ethers | ELILILLY AND COMPANY (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027185-A1 | Antithrombotic aromatic ethers | F2, F11, TFPI | GPR6 2624/4885PDE4B 1956/4885PDE4A 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.