Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043342 | 0.91 | MARS1 (0.40) | KMT2AMEN1SMN1; SMN2MAPTPOLB | |
| SCHEMBL13121815 | 0.83 | GSK3B (0.55) | KMT2AMEN1L3MBTL1SMN1; SMN2HTR3E | |
| SCHEMBL14043195 | 0.82 | NTRK1 (0.41) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL12954520 | 0.82 | GSK3B (0.43) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL14418659 | 0.80 | MAPT (0.40) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL14607070 | 0.78 | DRD2 (0.43) | KMT2AMEN1SMN1; SMN2MAPTBRD4 | |
| SCHEMBL14301238 | 0.78 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2MAPTPOLB | |
| SCHEMBL13289360 | 0.78 | ALDH1A1 (0.46) | KMT2AMEN1L3MBTL1MAPTPOLB | |
| SCHEMBL13121885 | 0.77 | GSK3B (0.56) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL14418710 | 0.77 | MEN1 (0.39) | KMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037824-A1 | Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors | SCHERING CORPORATION | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037824-A1 | Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors | CDK2, CDK5, CDKN1A | KMT2A 1000/4885MEN1 3389/4885L3MBTL1 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.