Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391402 | 0.81 | IAPP (0.45) | LPAR1CYSLTR2CYSLTR1KMT2ALMNA | |
| SCHEMBL4601121 | 0.80 | ALDH1A1 (0.42) | LPAR1CYSLTR2CYSLTR1KMT2ALMNA | |
| SCHEMBL14614108 | 0.80 | CYP4F2 (0.44) | LMNAGABRA1GABRB2THRATHRB | |
| SCHEMBL4601974 | 0.80 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL14220480 | 0.78 | GABRA1 (0.39) | LPAR1CYSLTR2CYSLTR1KMT2ALMNA | |
| SCHEMBL4601904 | 0.78 | SMN1; SMN2 (0.40) | LPAR1CYSLTR2CYSLTR1KMT2ALMNA | |
| SCHEMBL2441467 | 0.78 | NOTUM (0.48) | KMT2AMEN1MAPT | |
| SCHEMBL27850986 | 0.77 | IAPP (0.54) | CYSLTR2CYSLTR1SMN1; SMN2GABRA1GABRB2 | |
| SCHEMBL9308692 | 0.76 | TAAR1 (0.47) | SLC6A4 | |
| SCHEMBL27613400 | 0.74 | ALDH1A1 (0.48) | LPAR1KMT2ALMNAMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315750-B1 | CYCLIC PEPTIDES HAVING MELANOCORTIN-4 RECEPTOR AGONIST ACTIVITY | HOFFMANN LA ROCHE (CH) | 2007-02-14 | — | — | EP | disclosed |