Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951236 | 0.83 | LMNA (0.34) | CYP3A4ALDH1A1LMNA | |
| SCHEMBL5503012 | 0.83 | DDAH1 (0.33) | MAPT | |
| SCHEMBL5857517 | 0.74 | DDAH1 (0.33) | ALDH1A1 | |
| SCHEMBL9615298 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL3116666 | 0.73 | — | — | |
| SCHEMBL18710409 | 0.73 | — | — | |
| SCHEMBL1882200 | 0.72 | FAAH (0.37) | USP2CYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6905403 | 0.71 | — | — | |
| SCHEMBL7779029 | 0.71 | — | — | |
| SCHEMBL6905406 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754700-A2 | Synthesis of oligoketides | Kosan Biosciences, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |