Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14584046 | 0.81 | GPR3 (0.46) | GPR3KDM4EALDH1A1LMNATSHR | |
| SCHEMBL11726453 | 0.81 | GPR3 (0.46) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL11716790 | 0.74 | GPR3 (0.39) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL24188617 | 0.74 | GPR3 (0.39) | GPR3KDM4EHTTALDH1A1TSHR | |
| SCHEMBL11717839 | 0.72 | ALDH1A1 (0.51) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL11719930 | 0.69 | POLB (0.44) | KDM4EHTTALDH1A1LMNATSHR | |
| SCHEMBL24924297 | 0.66 | TP53 (0.36) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL11723137 | 0.64 | KDM4E (0.51) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL13542540 | 0.63 | GPR3 (0.52) | GPR3KDM4EHTTALDH1A1LMNA | |
| SCHEMBL7710952 | 0.63 | KDM4E (0.58) | GPR3KDM4EHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043057-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043057-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | GPR3 3070/4885KDM4E 4589/4885HTT 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.