SCHEMBL92072

SCHEMBL92072

O=C1NC(c2ccc(-c3ccccc3)cc2)=C2C(=O)NC(c3ccc(Cl)cc3)=C12

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
GSK3B P49841 9/20 0.53
PTGS2 P35354 5/20 0.44
LMNA P02545 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 1/20 0.40
CTRC Q99895 1/20 0.39
TDP2 O95551 1/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557806 0.98 GSK3B (0.54) CYP1A2GSK3BPTGS2LMNAGAA
SCHEMBL91966 0.90 PTGS2 (0.50) GSK3BPTGS2GAAMAPTTDP2
SCHEMBL91967 0.90 PTGS2 (0.48) GSK3BPTGS2CTRCTDP2
SCHEMBL7754290 0.90 PTGS2 (0.48) GSK3BPTGS2CTRCTDP2
SCHEMBL278635 0.86 GSK3B (0.48) GSK3BPTGS2LMNAGAAMAPT
SCHEMBL13204641 0.84 GSK3B (0.52) GSK3BTDP2
SCHEMBL3816794 0.82 GSK3B (0.67) CYP1A2GSK3BPTGS2
SCHEMBL10607586 0.82 GSK3B (0.54) GSK3BGAAMAPTTDP2
SCHEMBL7753950 0.81 CYP2D6 (0.46) GSK3BPTGS2LMNAMAPT
SCHEMBL21419776 0.81 GSK3B (0.58) GSK3BPTGS2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220308446-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-09-29 US disclosed
EP-2236562-B1 PIGMENT COMPOSITION FOR RED COLOR FILTER, METHOD FOR PRODUCING THE SAME, COLOR COMPOSITION USING THE SAME, AND COLOR FILTER TOYO INK MFG CO (JP) 2018-10-10 EP disclosed
EP-2146230-B1 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-09-12 EP disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
EP-2205682-B1 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE BVI LTD (VG) 2011-03-09 EP disclosed
EP-2236562-A1 PIGMENT COMPOSITION FOR RED COLOR FILTER, METHOD FOR PRODUCING THE SAME, COLOR COMPOSITION USING THE SAME, AND COLOR FILTER Toyo Ink Mfg. Co., Ltd (JP) 2010-10-06 EP disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
EP-2146230-A2 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
WO-2009049736-A2 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE (BVI) LIMITED (VG) 2009-04-23 WO disclosed
EP-0765919-B1 Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host CIBA SC HOLDING AG (CH) 2001-02-21 EP disclosed
US-5756746-A KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-05-26 US disclosed
EP-0765919-A2 Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host Ciba SC Holding AG (CH) 1997-04-02 EP disclosed