Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477725 | 0.90 | MAOA (0.63) | MAOAMAOBPDPK1SLC6A2SLC6A4 | |
| SCHEMBL13853630 | 0.90 | MAOA (0.63) | MAOAMAOBPDPK1SLC6A2SLC6A4 | |
| SCHEMBL11600879 | 0.81 | TAS1R3 (0.54) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3985112 | 0.80 | PDPK1 (0.46) | MAOAMAOBPDPK1ACHE | |
| SCHEMBL19521127 | 0.80 | PDPK1 (0.46) | MAOAMAOBPDPK1TAS1R3TAS1R1 | |
| SCHEMBL2804566 | 0.80 | TAS1R3 (0.55) | MAOAMAOBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8312130 | 0.78 | CTSD (0.47) | PDPK1ACHE | |
| SCHEMBL4981817 | 0.77 | ESR1 (0.46) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6409578 | 0.75 | ESR1 (0.47) | MAOAMAOBESR1ESR2 | |
| SCHEMBL61095 | 0.75 | PDPK1 (0.79) | PDPK1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |