Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891870 | 0.83 | PDE3B (0.39) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL12891871 | 0.83 | PDE3B (0.39) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL1240193 | 0.82 | TRPV1 (0.43) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL1856820 | 0.78 | TRPV1 (0.40) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL1857399 | 0.72 | MEN1 (0.38) | GAAKDM4EMEN1KMT2ATSHR | |
| SCHEMBL1240477 | 0.71 | ALDH1A1 (0.42) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL1998740 | 0.71 | DRD2 (0.41) | — | |
| SCHEMBL23976418 | 0.68 | KDM1A (0.49) | — | |
| SCHEMBL518971 | 0.68 | LGMN (0.54) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL1865468 | 0.68 | KEAP1 (0.41) | MAPTALDH1A1KDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |