Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615599 | 0.83 | CES2 (0.46) | CES2CYP1A2MAPTRXFP1KDM4E | |
| SCHEMBL9128943 | 0.82 | MTNR1A (0.53) | CES2CYP1A2MAPTKDM4EALDH1A1 | |
| SCHEMBL6198665 | 0.80 | CES2 (0.54) | CES2CYP1A2MAPTRXFP1KDM4E | |
| SCHEMBL761158 | 0.80 | KDM4E (0.61) | CES2CYP1A2MAPTRXFP1KDM4E | |
| SCHEMBL2746004 | 0.79 | MAPT (0.65) | CYP1A2MAPTKDM4EALDH1A1POLB | |
| SCHEMBL2732841 | 0.79 | CYP1A2 (0.58) | CES2CYP1A2MAPTRXFP1KDM4E | |
| SCHEMBL3240006 | 0.78 | CES2 (0.66) | CES2CYP1A2MAPTRXFP1KDM4E | |
| SCHEMBL13652571 | 0.78 | MTNR1A (0.62) | CES2MAPTRXFP1KDM4EALDH1A1 | |
| SCHEMBL2745224 | 0.77 | KDM4E (0.62) | CYP1A2MAPTKDM4EGAA | |
| SCHEMBL2746054 | 0.77 | SMN1; SMN2 (0.65) | KDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014258-A2 | GROWTH HORMONE SECRETAGOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2007-02-01 | — | — | WO | disclosed |