Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615486 | 0.83 | CES2 (0.52) | CES2MAPTRXFP1CYP1A2KDM4E | |
| SCHEMBL761158 | 0.74 | KDM4E (0.61) | CES2MAPTRXFP1CYP1A2KDM4E | |
| SCHEMBL6198665 | 0.74 | CES2 (0.54) | CES2MAPTRXFP1CYP1A2MC4R | |
| SCHEMBL12251060 | 0.73 | CYP1A2 (0.50) | CES2CASRCYP1A2CYP2A6SIGMAR1 | |
| SCHEMBL2732841 | 0.72 | CYP1A2 (0.58) | CES2MAPTRXFP1CYP1A2KDM4E | |
| SCHEMBL14748080 | 0.72 | FCER2 (0.55) | MC4RMC3R | |
| SCHEMBL3240006 | 0.72 | CES2 (0.66) | CES2MAPTRXFP1CYP1A2KDM4E | |
| SCHEMBL13652571 | 0.72 | MTNR1A (0.62) | CES2MAPTRXFP1KDM4EALDH1A1 | |
| SCHEMBL11822095 | 0.72 | CYP1A2 (0.52) | CYP1A2CYP2A6SIGMAR1MC4RMC5R | |
| SCHEMBL2255106 | 0.71 | HDAC1 (0.53) | CES2CYP1A2CYP2A6SIGMAR1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014258-A2 | GROWTH HORMONE SECRETAGOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2007-02-01 | — | — | WO | disclosed |