Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 6/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26607564 | 0.83 | KDM4E (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL24682199 | 0.80 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL26622982 | 0.79 | KDM4E (0.36) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL26638943 | 0.76 | KDM4E (0.34) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL2983374 | 0.76 | DYRK1A (0.46) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL26607533 | 0.75 | KDM4E (0.34) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL27303515 | 0.73 | HDAC6 (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL28384782 | 0.73 | KDM4E (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL18310595 | 0.72 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL3144585 | 0.72 | HDAC6 (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795192-B2 | Antimicrobial compounds, compositions, and uses thereof | Lakewood Amedex, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11795192-B2 | Antimicrobial compounds, compositions, and uses thereof | Lakewood Amedex, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11203610-B2 | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2021-12-21 | — | — | US | disclosed |
| US-20210230680-A1 | Modified Nucleobases with Uniform H-Bonding Interactions, Homo- and Hetero-Basepair Bias, and Mismatch Discrimination | CARNEGIE MELLON UNIVERSITY | 2021-07-29 | — | — | US | disclosed |
| US-20190185510-A1 | 2'3' CYCLIC DINUCLEOTIDES WITH PHOSPHONATE BOND ACTIVATING THE STING ADAPTOR PROTEIN | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-06-20 | — | — | US | disclosed |
| US-20190185509-A1 | 2'2' CYCLIC DINUCLEOTIDES WITH PHOSPHONATE BOND ACTIVATING THE STING ADAPTOR PROTEIN | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-06-20 | — | — | US | disclosed |
| US-20130018018-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | Epiphany Biosciences ,Inc. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230680-A1 | Modified Nucleobases with Uniform H-Bonding Interactions, Homo- and Hetero-Basepair Bias, and Mismatch Discrimination | POLL, PNKP, POLM | PI4KA 2047/4885PI4K2B 2079/4885PI4K2A 1926/4885 |
| US-20130018018-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | PNP, TYMP, ENTPD5 | PI4KA 287/4885PI4K2B 383/4885PI4K2A 315/4885 |
| US-20190185509-A1 | 2'2' CYCLIC DINUCLEOTIDES WITH PHOSPHONATE BOND ACTIVATING THE STING ADAPTOR PROTEIN | STING1, CGAS, TBK1 | PI4KA 646/4885PI4K2B 390/4885PI4K2A 386/4885 |
| US-11203610-B2 | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein | STING1, CGAS, IRF3 | PI4KA 414/4885PI4K2B 306/4885PI4K2A 308/4885 |
| US-20190185510-A1 | 2'3' CYCLIC DINUCLEOTIDES WITH PHOSPHONATE BOND ACTIVATING THE STING ADAPTOR PROTEIN | STING1, CGAS, IRF3 | PI4KA 440/4885PI4K2B 313/4885PI4K2A 314/4885 |
| US-11795192-B2 | Antimicrobial compounds, compositions, and uses thereof | CAT, MPO, NISCH | PI4KA 1930/4885PI4K2B 2372/4885PI4K2A 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.