Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332153 | 0.86 | NPSR1 (0.46) | HPGDNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL13919830 | 0.80 | ALDH1A1 (0.54) | HPGDNPSR1PLK1MEN1KMT2A | |
| SCHEMBL10268332 | 0.77 | HPGD (0.64) | HPGDNPSR1PLK1KMT2AALDH1A1 | |
| SCHEMBL12332295 | 0.76 | ADRB2 (0.41) | HPGDNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL12332426 | 0.75 | PLK1 (0.58) | HPGDNPSR1PLK1MEN1KMT2A | |
| SCHEMBL17208757 | 0.74 | PLK1 (0.59) | HPGDNPSR1PLK1MEN1KMT2A | |
| SCHEMBL12358256 | 0.73 | MTNR1A (0.45) | ALDH1A1MAPK1 | |
| SCHEMBL16309295 | 0.73 | TSHR (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18469618 | 0.73 | TDP1 (0.61) | HPGDNPSR1PLK1MEN1KMT2A | |
| SCHEMBL13159542 | 0.72 | CYP4F2 (0.39) | HPGDPLK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Abbott Medical Optics Inc. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | CRY1, AAAS, CYBA | HPGD 491/4885NPSR1 4572/4885PLK1 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.