Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413945 | 1.00 | FFAR1 (0.31) | FFAR1ALDH1A1MAPTCYP19A1RXRA | |
| SCHEMBL29339536 | 0.87 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL29338902 | 0.87 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL317978 | 0.86 | TRPA1 (0.33) | ALDH1A1 | |
| SCHEMBL17383169 | 0.82 | ALDH1A1 (0.32) | FFAR1ALDH1A1MAPTCYP19A1RXRA | |
| SCHEMBL15835829 | 0.80 | KDM5A (0.32) | SIGMAR1 | |
| SCHEMBL18900691 | 0.79 | FAAH (0.50) | MAPTCYP19A1PPARG | |
| SCHEMBL19288792 | 0.78 | — | — | |
| SCHEMBL23433550 | 0.78 | ALDH1A1 (0.47) | FFAR1ALDH1A1MAPTCYP19A1RXRA | |
| SCHEMBL14045112 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100764-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-7173004-B2 | Macrocyclic isoquinoline peptide inhibitors of hepatitis C virus | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |