Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.40 |
| ▸ | PPID | Q08752 | 4/20 | 0.39 |
| ▸ | PPIG | Q13427 | 2/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100114 | 0.78 | TPSAB1 (0.50) | PPIBEPHX2PPIDPPIGPPIA | |
| SCHEMBL14619100 | 0.78 | PPIB (0.43) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL23116511 | 0.70 | PPIB (0.44) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL1800569 | 0.67 | KMT2A (0.63) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL15939528 | 0.66 | PPID (0.65) | PPIBEPHX2PPIDPPIGPPIA | |
| SCHEMBL258716 | 0.66 | CYP2C9 (0.62) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL15940349 | 0.66 | ALOX12 (0.65) | LMNA | |
| Hydrochloric Acid SCHEMBL10744056 | 0.66 | KMT2A (0.61) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL13562878 | 0.66 | PPIB (0.41) | PPIBEPHX2ITGB1ITGA5PPID | |
| SCHEMBL6881708 | 0.65 | EPHX2 (0.45) | PPIBEPHX2PPIDPPIGPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007018941-A2 | PYRIMIDYL-THIOPHENE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-15 | — | — | WO | disclosed |