Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | PPIB | P23284 | 2/20 | 0.53 |
| ▸ | PPID | Q08752 | 2/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | PPIG | Q13427 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10744056 | 0.98 | KMT2A (0.61) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL12133623 | 0.89 | KMT2A (0.76) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL5945697 | 0.87 | KMT2A (0.50) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| Aniline SCHEMBL27372056 | 0.85 | CYP2C9 (0.56) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL24541407 | 0.84 | KMT2A (0.59) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL8404729 | 0.83 | TPSAB1 (0.68) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL5945692 | 0.83 | EPHX2 (0.59) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL15939528 | 0.83 | PPID (0.65) | KMT2AEPHX2PPIBPPIDPPIA | |
| SCHEMBL258716 | 0.83 | CYP2C9 (0.62) | KMT2AALDH1A1MAPTEPHX2PPIB | |
| SCHEMBL6415716 | 0.81 | EPHX2 (0.50) | KMT2AHDAC1HDAC6ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | ASTEX TECHNOLOGY, INC. (GB) | 2006-06-22 | — | — | US | claimed |
| JP-2006500348-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1534685-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | Astex Technology Limited (GB) | 2005-06-01 | — | — | EP | claimed |
| WO-2004014864-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
| EP-2788359-B1 | COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS | RES TRIANGLE INST (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9187453-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| US-9150582-B2 | Composition and method for neuropeptide S receptor (NPSR) antagonists | RESEARCH TRIANGLE INSTITUTE (US) | 2015-10-06 | — | — | US | disclosed |
| CN-102459165-B | Antiviral compound | ABBVIE (US) | 2015-09-02 | — | — | CN | disclosed |
| EP-1224170-A1 | 6-POSITION SUBSTITUTED INDOLINE, PRODUCTION AND USE THEREOF AS A MEDICAMENT | Boehringer Ingelheim Pharma KG (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027081-A1 | 6-POSITION SUBSTITUTED INDOLINE, PRODUCTION AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-04-19 | — | — | WO | disclosed |
| EP-0418385-B1 | BENZOTRIAZOLE DERIVATIVES AND REAGENTS CONTAINING SAME FOR ANALYZING CARBOXYLIC ACIDS | SHIONOGI & CO (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5097040-A | Existing as metabolites of carbohydrates, lipids, proteins | SHIONOGI & CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0418385-A1 | BENZOTRIAZOLE DERIVATIVES AND REAGENTS CONTAINING SAME FOR ANALYZING CARBOXYLIC ACIDS | SHIONOGI & CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |
| EP-0038453-B1 | PROCESS FOR THE PREPARATION OF WATER SOLUBLE PHTHALOCYANINE DYESTUFFS | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0038453-A2 | Process for the preparation of water soluble phthalocyanine dyestuffs | BAYER AG (DE) | 1981-10-28 | — | — | EP | disclosed |
| US-4010200-A | FOR DYEING LIVE HUMAN HAIR | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | KMT2A 4575/4885HDAC1 1903/4885HDAC6 193/4885 |
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | KMT2A 1669/4885HDAC1 52/4885HDAC6 56/4885 |
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | CCNC, CDK1, CDK7 | KMT2A 1773/4885HDAC1 318/4885HDAC6 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.