Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21768959 | 0.87 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL18403610 | 0.86 | LMNA (0.43) | LMNATHRBALDH1A1TSHRMAPK1 | |
| SCHEMBL31506492 | 0.81 | LMNA (0.39) | LMNATHRBTSHR | |
| SCHEMBL4498980 | 0.81 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL14619484 | 0.80 | LMNA (0.43) | LMNATHRB | |
| SCHEMBL28108718 | 0.78 | DNM1 (0.37) | — | |
| SCHEMBL3682858 | 0.76 | LMNA (0.35) | LMNATHRBALDH1A1 | |
| SCHEMBL10016143 | 0.74 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL12124909 | 0.73 | — | — | |
| SCHEMBL12332004 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373696-A2 | CATALYST COMPOSITION WITH PHOSPHORUS-BASED DONOR | Dow Global Technologies LLC (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010078330-A2 | CATALYST COMPOSITION WITH PHOSPHORUS-BASED DONOR AND METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| EP-0361494-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1990-04-04 | — | — | EP | disclosed |