Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541926 | 0.96 | CA4 (0.36) | CA1CA4FAHD1 | |
| SCHEMBL1706124 | 0.96 | — | — | |
| SCHEMBL9578850 | 0.92 | — | — | |
| SCHEMBL15064728 | 0.92 | CA1 (0.33) | CA1CA4FAHD1 | |
| SCHEMBL526233 | 0.87 | — | — | |
| Potassium Ion SCHEMBL1124622 | 0.87 | — | — | |
| SCHEMBL10459297 | 0.87 | — | — | |
| SCHEMBL4359131 | 0.87 | CA4 (0.36) | CA1CA4FAHD1 | |
| Zinc Ion SCHEMBL6294528 | 0.87 | — | — | |
| SCHEMBL138247 | 0.87 | CA4 (0.36) | CA1CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573475-B1 | BASIC CALCIUM ALUMINIUM HYDROXIDE DICARBOXYLATES, METHOD FOR PREPARING THEM AND USE THEREOF | BAERLOCHER GMBH (DE) | 1996-05-08 | — | — | EP | claimed |
| EP-2470592-B1 | PROCESS FOR FORMULATING STABILIZER MELTS, SHAPED BODIES PRODUCED THEREBY AND USE THEREOF | BAERLOCHER GMBH (DE) | 2016-10-12 | — | — | EP | disclosed |
| EP-2470592-A1 | PROCESS FOR FORMULATING STABILIZER MELTS, SHAPED BODIES PRODUCED THEREBY AND USE THEREOF | Baerlocher GmbH (DE) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011023402-A1 | PROCESS FOR FORMULATING STABILIZER MELTS, SHAPED BODIES PRODUCED THEREBY AND USE THEREOF | BAERLOCHER GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |