Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620051 | 0.86 | EPHX1 (0.35) | EPHX1GID4ADRA2AADRA1ACYP2D6 | |
| SCHEMBL14620055 | 0.76 | ALDH1A1 (0.39) | ADRA1AALDH1A1KMT2ATSHR | |
| SCHEMBL14620266 | 0.74 | ALDH1A1 (0.38) | ADRA1AALDH1A1KMT2ATSHR | |
| SCHEMBL14620045 | 0.70 | EPHX1 (0.41) | EPHX1GID4ADRA2AADRA1ACYP2D6 | |
| SCHEMBL14479769 | 0.70 | ALDH1A1 (0.34) | ADRA1AALDH1A1MAPK1 | |
| SCHEMBL8070410 | 0.69 | HAO1 (0.52) | EPHX1GID4ADRA2AADRA1ACYP2D6 | |
| SCHEMBL14620057 | 0.69 | DRD1 (0.35) | ALDH1A1MAPK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14620183 | 0.69 | ALDH1A1 (0.33) | ADRA1AALDH1A1 | |
| SCHEMBL14620060 | 0.66 | CYP1B1 (0.34) | ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3668028 | 0.65 | ADRA2A (0.54) | GID4ADRA2AADRA1ACYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |