Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620183 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14620182 | 0.78 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL14620055 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AALDH1A1APPBACE1 | |
| SCHEMBL14620044 | 0.76 | MAOA (0.36) | DRD1DRD5SMN1; SMN2MT-CO2ALOX5 | |
| SCHEMBL14620266 | 0.76 | ALDH1A1 (0.38) | KMT2AALDH1A1APPBACE1BACE2 | |
| SCHEMBL14620181 | 0.76 | MGLL (0.48) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL14479769 | 0.72 | ALDH1A1 (0.34) | ALDH1A1APPBACE1BACE2MAPK1 | |
| SCHEMBL14620064 | 0.69 | EPHX1 (0.39) | KMT2AMEN1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL14620039 | 0.69 | — | — | |
| SCHEMBL14620054 | 0.68 | ALDH1A1 (0.51) | SMN1; SMN2MT-CO2ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |