Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.84 |
| ▸ | HTT | P42858 | 6/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | ATM | Q13315 | 1/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | GFER | P55789 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560453 | 0.83 | LMNA (0.75) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31575415 | 0.83 | SMN1; SMN2 (0.65) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31575433 | 0.82 | RAB9A (0.63) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL17786245 | 0.82 | SMN1; SMN2 (0.71) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8259965 | 0.82 | TSHR (0.80) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31575414 | 0.81 | RAB9A (0.78) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL17786270 | 0.80 | LMNA (0.64) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL31575430 | 0.78 | HIF1A (0.68) | LMNAHTTSMN1; SMN2TP53RAB9A | |
| SCHEMBL16079521 | 0.78 | TP53 (0.82) | LMNAHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13939659 | 0.77 | ALDH1A1 (0.80) | LMNAHTTSMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008541-A2 | CELLULAR CHOLESTEROL ABSORPTION MODIFIERS | KALYPSYS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |