Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624611 | 0.77 | HSD17B10 (0.40) | HSD17B10ALDH1A1TP53MAPTHPGD | |
| SCHEMBL10017673 | 0.76 | PLA2G1B (0.60) | PLA2G1BATG4BHSD17B10ALDH1A1MAPT | |
| SCHEMBL21622362 | 0.69 | HSD17B10 (0.42) | HSD17B10ALDH1A1TP53MAPTHPGD | |
| SCHEMBL7028416 | 0.68 | ALDH1A1 (0.34) | PLA2G1BATG4BHSD17B10ALDH1A1TP53 | |
| SCHEMBL13984089 | 0.65 | L3MBTL1 (0.41) | PLA2G1BATG4BHSD17B10ALDH1A1TP53 | |
| SCHEMBL3139516 | 0.64 | L3MBTL1 (0.49) | PLA2G1BATG4BALDH1A1MAPTHPGD | |
| SCHEMBL516264 | 0.63 | PLA2G1B (0.41) | PLA2G1BATG4BHSD17B10ALDH1A1TP53 | |
| SCHEMBL3153974 | 0.62 | PLA2G1B (0.38) | PLA2G1BATG4BHSD17B10ALDH1A1TP53 | |
| SCHEMBL1922260 | 0.62 | PLA2G1B (0.43) | PLA2G1BATG4BHSD17B10ALDH1A1TP53 | |
| SCHEMBL9095862 | 0.62 | MAPT (0.40) | HSD17B10ALDH1A1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010515-A1 | IMPROVEMENTS TO ANALOGOUS COMPOUNDS OF 6-THIOGUANOSINE TRIPHOSPHATE, THEIR USE IN MEDICAL FIELDS AND PROCESSES FOR THEIR PREPARATION | GIULIANI INTERNATIONAL LIMITED (IE) | 2007-01-25 | — | — | WO | disclosed |