Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922086 | 0.84 | L3MBTL1 (0.56) | L3MBTL1ADORA2AALDH1A1KMT2AMEN1 | |
| SCHEMBL18430411 | 0.82 | L3MBTL1 (0.54) | L3MBTL1RXFP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL516264 | 0.79 | PLA2G1B (0.41) | L3MBTL1ADORA2ARXFP1PLA2G1BATG4B | |
| SCHEMBL1922260 | 0.78 | PLA2G1B (0.43) | L3MBTL1ADORA2ARXFP1PLA2G1BATG4B | |
| SCHEMBL18430437 | 0.77 | ALDH1A1 (0.50) | ADORA2ARXFP1PLA2G1BATG4BALDH1A1 | |
| SCHEMBL1289601 | 0.77 | L3MBTL1 (0.41) | L3MBTL1ADORA2ARXFP1PLA2G1BATG4B | |
| SCHEMBL1923354 | 0.75 | L3MBTL1 (0.40) | L3MBTL1ADORA2ARXFP1PLA2G1BATG4B | |
| SCHEMBL27469752 | 0.74 | KMT2A (0.40) | L3MBTL1ADORA2ARXFP1PLA2G1BATG4B | |
| SCHEMBL7979698 | 0.74 | ALDH1A1 (0.46) | L3MBTL1ADORA2ARXFP1ALDH1A1KMT2A | |
| SCHEMBL6555490 | 0.74 | L3MBTL1 (0.48) | L3MBTL1ADORA2AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462714-B2 | Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates | LES LABORATOIRES SERVIER (FR) | 2008-12-09 | — | — | US | disclosed |
| US-7238815-B2 | Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates | LES LABORATOIRES SERVIER (FR) | 2007-07-03 | — | — | US | disclosed |