Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590643 | 0.82 | NAMPT (0.55) | NAMPTHPGDPOLBHTT | |
| SCHEMBL13236584 | 0.76 | ALDH1A1 (0.50) | NAMPTPOLBKDM4EALDH1A1 | |
| SCHEMBL14625863 | 0.74 | HSD17B3 (0.50) | NAMPTPOLBKDM4EALDH1A1 | |
| SCHEMBL6622210 | 0.74 | HPGD (0.54) | NAMPTHPGDPOLBHTTKDM4E | |
| SCHEMBL620074 | 0.71 | POLB (0.66) | HPGDPOLBHTTKDM4EALDH1A1 | |
| SCHEMBL3710047 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL14626051 | 0.71 | AKR1C3 (0.42) | HPGDALDH1A1MAPK14 | |
| SCHEMBL19609464 | 0.70 | HDAC6 (0.54) | — | |
| SCHEMBL19339187 | 0.70 | TERT (0.51) | NAMPT | |
| SCHEMBL14626151 | 0.70 | HPGD (0.51) | HPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |