SCHEMBL14626482

SCHEMBL14626482

Cc1cc(N)ccc1Oc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.43
PDE10A Q9Y233 1/20 0.43
TAAR5 O14804 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
PGR P06401 2/20 0.41
AR P10275 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR1 P03372 1/20 0.41
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TNIK Q9UKE5 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
ABL1 P00519 1/20 0.40
ABCB1 P08183 1/20 0.40
BCR P11274 1/20 0.40
TEAD4 Q15561 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13683235 0.95 PDE10A (0.47) ESR2PDE10ATAAR5TAAR1PGR
SCHEMBL2989217 0.92 ALDH1A1 (0.47) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL2992329 0.86 ALDH1A1 (0.52) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29688467 0.84 ALDH1A1 (0.55) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3003478 0.84 ALDH1A1 (0.55) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL31457276 0.84 ALDH1A1 (0.55) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL1155719 0.84 ALDH1A1 (0.55) PDE10AMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL28091759 0.83 ESR2 (0.46) ESR2PGRARMEN1KMT2A
SCHEMBL7020062 0.83 ALDH1A1 (0.46) ESR2TAAR5TAAR1MEN1KMT2A
SCHEMBL8915293 0.81 ALDH1A1 (0.53) MEN1KMT2AALDH1A1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO disclosed