Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CCNH | P51946 | 2/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658224 | 0.80 | PIM1 (0.55) | MAPTHTTALPLNR4A2CREBBP | |
| SCHEMBL14215611 | 0.78 | NR4A2 (0.43) | MAPTHTTALPLNR4A2MEN1 | |
| Lycogarubin C SCHEMBL12658123 | 0.78 | NR4A2 (0.59) | MAPTHTTALPLNR4A2CREBBP | |
| Lycogarubin C SCHEMBL30742812 | 0.78 | NR4A2 (0.59) | MAPTHTTALPLNR4A2CREBBP | |
| SCHEMBL14628490 | 0.74 | HTR2A (0.40) | MAPTHTTALPLMEN1KMT2A | |
| Lycogarubin B SCHEMBL31061720 | 0.70 | HTT (0.50) | MAPTHTTALPLNR4A2CREBBP | |
| SCHEMBL12658127 | 0.70 | NR4A2 (0.57) | MAPTHTTALPLNR4A2CREBBP | |
| Lynamicin E SCHEMBL12658018 | 0.69 | NR4A2 (0.56) | MAPTHTTALPLNR4A2CREBBP | |
| SCHEMBL12658025 | 0.69 | ALPL (0.49) | MAPTHTTALPLNR4A2CREBBP | |
| SCHEMBL12658122 | 0.69 | MAPT (0.49) | MAPTHTTALPLNR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |