SCHEMBL1462833

SCHEMBL1462833

CCC(C(=O)O)N1CCC(=O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
SLC6A2 P23975 3/20 0.39
SLC6A3 Q01959 3/20 0.39
SLC6A4 P31645 1/20 0.39
ALDH1A1 P00352 1/20 0.34
PKM P14618 1/20 0.34
HSD17B10 Q99714 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3102765 0.83
SCHEMBL1462962 0.82 CA2 (0.39) CA2SLC6A2SLC6A3SLC6A4ACE
SCHEMBL10867510 0.80 LMNA (0.39) LMNACA12CA1CA2CA3
SCHEMBL499846 0.79 SLC6A3 (0.50) SLC6A2SLC6A3SLC6A4
SCHEMBL4441694 0.79 SLC6A3 (0.50) SLC6A2SLC6A3SLC6A4
SCHEMBL8529806 0.79 SLC6A3 (0.46) LMNACA12CA1CA2CA3
SCHEMBL19889439 0.79 SLC6A3 (0.46) LMNACA12CA1CA2CA3
SCHEMBL6422005 0.79 SLC6A2 (0.38) LMNACA12CA1CA2CA3
SCHEMBL3721702 0.79 LMNA (0.45) LMNASLC6A2SLC6A3SLC6A4ALDH1A1
SCHEMBL472291 0.78 SLC6A3 (0.49) SLC6A2SLC6A3SLC6A4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018160521-A2 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN Lazuli, Inc. (US) 2018-09-07 WO disclosed
US-20110071286-A1 NOVEL PREPARATION PROCESS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071286-A1 NOVEL PREPARATION PROCESS RPLP1, RPLP2, CYP1B1 LMNA 1459/4885CA12 2950/4885CA1 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.