Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13310700 | 0.81 | GSK3B (0.58) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL21998520 | 0.81 | AKR1B10 (0.67) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL14629577 | 0.76 | TRPV1 (0.52) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL1573468 | 0.76 | AKR1B10 (0.69) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL1573466 | 0.76 | AKR1B10 (0.69) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL13311577 | 0.75 | GSK3B (0.65) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| Letestuianin A SCHEMBL29565897 | 0.74 | HTR1A (0.62) | AKR1B1MAOBPTGS2GLO1CAMK2A | |
| SCHEMBL29565226 | 0.74 | HTR1A (0.69) | AKR1B1MAOBPTGS2GLO1CAMK2A | |
| SCHEMBL31237229 | 0.74 | AKR1B10 (0.51) | AKR1B1MAOBAKR1B10PTGS2GLO1 | |
| SCHEMBL30661993 | 0.74 | AKR1B10 (0.51) | AKR1B1MAOBAKR1B10PTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | KIM DARRICK S H | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | APP, BACE1, GSAP | AKR1B1 3323/4885MAOB 1411/4885AKR1B10 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.