Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479868 | 0.94 | MEN1 (0.40) | KMT2AMEN1RXFP1MAPTRAB9A | |
| SCHEMBL1845080 | 0.93 | KEAP1 (0.38) | KMT2AMEN1RXFP1MAPTRAB9A | |
| SCHEMBL5551024 | 0.93 | KMT2A (0.42) | KMT2AMEN1RXFP1MAPTRAB9A | |
| SCHEMBL5550214 | 0.92 | KMT2A (0.47) | KMT2AMEN1RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL7938728 | 0.92 | SLC16A3 (0.42) | KMT2AMEN1RXFP1MAPTRAB9A | |
| SCHEMBL5550993 | 0.90 | MAPT (0.38) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL5549293 | 0.86 | MAPT (0.39) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL5645606 | 0.85 | MAPT (0.35) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1848196 | 0.85 | PLA2G2A (0.41) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7936515 | 0.85 | KEAP1 (0.42) | KMT2AMAPTRAB9AKDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971914-B1 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO 1,2-b PYRANS AND HETEROCYCLIC PYRANS | VIVIMED LABS EUROP LTD (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |