Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845404 | 0.94 | KMT2A (0.43) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL5645606 | 0.90 | MAPT (0.35) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5650444 | 0.89 | MAPT (0.38) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL1845080 | 0.88 | KEAP1 (0.38) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL5551024 | 0.87 | KMT2A (0.42) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL5550214 | 0.87 | KMT2A (0.47) | MEN1KMT2ARXFP1MAPTSMN1; SMN2 | |
| SCHEMBL7938728 | 0.87 | SLC16A3 (0.42) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL1847688 | 0.86 | GABRG2 (0.37) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7483443 | 0.86 | LRP6 (0.34) | MEN1KMT2ARXFP1MAPTRAB9A | |
| SCHEMBL5550993 | 0.84 | MAPT (0.38) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117656-B1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LTD (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6387512-B1 | FOR COLORING INKS, FUELS, PLASTICS OR GLASS | JAMES ROBINSON LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |