Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3330717 | 0.89 | BCL2L1 (0.45) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL2390084 | 0.87 | ALDH1A1 (0.46) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL5736088 | 0.87 | LMNA (0.50) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL1846303 | 0.86 | KDM4E (0.47) | CA12CA2CA7CA9CA14 | |
| SCHEMBL3328123 | 0.85 | HTT (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2049629 | 0.85 | RAB9A (0.42) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL11124197 | 0.83 | MAPT (0.49) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL16479442 | 0.80 | ALDH1A1 (0.54) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL28659794 | 0.80 | CA12 (0.48) | PTPN11CA12CA1CA2CA7 | |
| SCHEMBL13005288 | 0.79 | ALDH1A1 (0.43) | PTPN11CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |