SCHEMBL14630982

SCHEMBL14630982

CC1CC(n2cnc(CC(CCCN)C(=O)O)c2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 20/20 1.00
CPB1 P15086 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333990 0.91 CPB2 (1.00) CPB2
SCHEMBL14630901 0.90 CPB2 (1.00) CPB2
SCHEMBL14631117 0.90 CPB2 (1.00) CPB2
SCHEMBL14630900 0.90 CPB2 (1.00) CPB2
SCHEMBL14631503 0.90 CPB2 (1.00) CPB2
SCHEMBL14631442 0.90 CPB2 (1.00) CPB2
SCHEMBL14631441 0.90 CPB2 (1.00) CPB2
SCHEMBL14631502 0.90 CPB2 (1.00) CPB2
SCHEMBL14631108 0.90 CPB2 (1.00) CPB2CPB1
SCHEMBL14631106 0.90 CPB2 (1.00) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2548871-B1 CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2017-07-19 EP claimed
US-9340531-B2 Cycloalkyl-substituted imidazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-05-17 US claimed
US-20140178349-A1 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-06-26 US claimed
US-20130230501-A9 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-05 US claimed
US-20130022587-A1 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-24 US claimed
EP-2548871-A1 CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-23 EP claimed
CN-105801489-B Cycloalkyl-substituted imidazole derivatives 第一三共株式会社 2019-12-10 CN disclosed
US-20190117624-A1 THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASES DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-04-25 US disclosed
US-20170368037-A1 PHARMACEUTICAL COMPOSITION FOR PROMOTION OF FIBRINOLYSIS DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-12-28 US disclosed
EP-3238721-A1 MEDICAL COMPOSITION FOR PROMOTING FIBRINOLYSIS DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-11-01 EP disclosed
EP-2548871-B1 CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2017-07-19 EP disclosed
US-9340531-B2 Cycloalkyl-substituted imidazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-05-17 US disclosed
US-9340531-B2 Cycloalkyl-substituted imidazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-05-17 US disclosed
US-20130230501-A9 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-05 US disclosed
US-20130230501-A9 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-05 US disclosed
US-20130230501-A9 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-05 US disclosed
US-20130022587-A1 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-24 US disclosed
US-20130022587-A1 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-24 US disclosed
US-20130022587-A1 Cycloalkyl-Substituted Imidazole Derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-24 US disclosed
EP-2548871-A1 CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130022587-A1 Cycloalkyl-Substituted Imidazole Derivative F7, F12, TFPI CPB2 258/4885CPB1 276/4885
US-20170368037-A1 PHARMACEUTICAL COMPOSITION FOR PROMOTION OF FIBRINOLYSIS TFPI, TFPI2, F11 CPB2 79/4885CPB1 100/4885
US-20130230501-A9 Cycloalkyl-Substituted Imidazole Derivative F7, F12, TFPI CPB2 258/4885CPB1 276/4885
US-20190117624-A1 THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASES FABP2, SI, SLC10A2 CPB2 3026/4885CPB1 3137/4885
US-20140178349-A1 Cycloalkyl-Substituted Imidazole Derivative F7, F12, TFPI CPB2 258/4885CPB1 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.