Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CASR | P41180 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764078 | 1.00 | KMT2A (0.65) | KMT2AKDM4ESMN1; SMN2ALDH1A1CASR | |
| SCHEMBL30311730 | 0.92 | TSHR (0.65) | KMT2AKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8503249 | 0.92 | TSHR (0.65) | KMT2AKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL14161046 | 0.89 | ADRA1A (0.55) | KMT2AKDM4ESMN1; SMN2ALDH1A1ADRA1A | |
| SCHEMBL27926165 | 0.89 | ALDH1A1 (0.60) | KMT2AKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL28639674 | 0.87 | KMT2A (0.57) | KMT2AKDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL31276974 | 0.86 | CYP1A2 (0.73) | KMT2AKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL12744507 | 0.85 | KMT2A (0.52) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31277216 | 0.84 | ADRA1A (0.54) | KMT2AKDM4ESMN1; SMN2ALDH1A1ADRA1A | |
| SCHEMBL31277167 | 0.83 | PARG (0.56) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115650924-A | Green synthesis method of quinazolinone | 上海橡实化学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113185468-B | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-113461617-A | Method for preparing N-heterocycle through visible light mediated dehydrogenation | 石河子大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-113185468-A | Method for synthesizing quinazolinone through photocatalysis | 上海橡实化学有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | disclosed |
| CN-103408502-A | Synthetic method of quinazolinone compounds | UNIV HUNAN | 2013-11-27 | — | — | CN | disclosed |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. | 2013-03-07 | — | — | US | disclosed |
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
| EP-2266962-A1 | THE COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2010-12-29 | — | — | EP | disclosed |
| CN-101531638-A | Compounds useful as estrogen-related receptor modulators and uses thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | KMT2A 1845/4885KDM4E 1222/4885SMN1; SMN2 4538/4885 |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | KMT2A 4200/4885KDM4E 4704/4885SMN1; SMN2 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.