Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563322 | 0.90 | RORC (0.41) | RORCTDP1HPGDRECQLALDH1A1 | |
| SCHEMBL2329831 | 0.83 | ALDH1A1 (0.44) | TDP1ALDH1A1GAAMAPK1MEN1 | |
| SCHEMBL5671783 | 0.81 | MGLL (0.37) | HPGDALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL6459702 | 0.80 | PTGDR2 (0.41) | HPGDRECQLALDH1A1TSHRMEN1 | |
| SCHEMBL6459325 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1GAAMEN1MAPT | |
| SCHEMBL12885646 | 0.75 | ALDH1A1 (0.57) | HPGDALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL14634986 | 0.74 | PTGDR2 (0.46) | HPGDALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL5673166 | 0.73 | ERAP2 (0.39) | HPGDALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL5223661 | 0.73 | ERAP2 (0.45) | HPGDALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL2327866 | 0.72 | PPARG (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023677-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| US-20130023677-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023677-A1 | PROCESS FOR PREPARING AMINOBENZOFURAN DERIVATIVES | CYP2F1, F5, F12 | RORC 4722/4885TDP1 2014/4885HPGD 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.