SCHEMBL14634355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6651709	0.84	CYP2A6 (0.50)	CYP2A6TLR4TLR2RAF1ERN1
	SCHEMBL6651703	0.84	CYP2A6 (0.50)	CYP2A6TLR4TLR2RAF1ERN1
	SCHEMBL2462770	0.82	CYP2A6 (0.67)	CYP2A6KDM4ELMNACCR1CCR5
	SCHEMBL6753903	0.81	CYP2A6 (0.49)	CYP2A6TLR4TLR2RAF1KDM4E
	Hydrochloric Acid SCHEMBL6004892	0.80	CYP2A6 (0.64)	CYP2A6KDM4ELMNACCR1CCR5
	SCHEMBL510345	0.79	TLR4 (0.61)	CYP2A6TLR4TLR2ERN1KDM4E
	SCHEMBL29442907	0.79	TLR4 (0.61)	CYP2A6TLR4TLR2ERN1KDM4E
	SCHEMBL10031169	0.78	CYP2A6 (0.62)	CYP2A6KDM4ELMNACCR1CCR5
	SCHEMBL29443808	0.77	KDM4E (0.50)	CYP2A6TLR4TLR2ERN1KDM4E
	SCHEMBL6290	0.77	KDM4E (0.50)	CYP2A6TLR4TLR2ERN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.