Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2250329 | 0.97 | MAOB (0.59) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL2245540 | 0.83 | ALDH1A1 (0.55) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL6620588 | 0.82 | BCHE (0.59) | DRD2MAOBHTR1ADRD3 | |
| SCHEMBL14028451 | 0.82 | HTR1A (0.79) | DRD2MAOBHTR1ADRD3 | |
| SCHEMBL5730330 | 0.81 | HTR1A (0.63) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL6619060 | 0.80 | MAOB (0.53) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL5730545 | 0.80 | DRD2 (0.55) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL29459507 | 0.80 | HTR1A (0.62) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL26992312 | 0.80 | HTR1A (0.62) | DRD2MAOBHTR1AHTR7HRH1 | |
| SCHEMBL3440240 | 0.79 | MAOB (0.73) | DRD2MAOBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | LUK KIN-CHUN | 2011-03-24 | — | — | US | disclosed |
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | LUK KIN-CHUN | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | FGFR3, FGFR4, FGFR1 | DRD2 3641/4885MAOB 2809/4885HTR1A 2177/4885 |
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | FGFR3, FGFR4, FGFR1 | DRD2 3641/4885MAOB 2809/4885HTR1A 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.